CpG ODN 2006 (Human TLR9 Agonist)

评测依据

• review_count：510
• rating_avg：4.6
• brand_reputation：0
• merchant_count：0
• price_range：[800,1999]
• dimension：best_quality
• sources：["京东","天猫","小红书","什么值得买"]
• time_range：{"from":"2026-06-25 15:17:17","to":"2026-06-25 15:17:17"}
• intros：{"brand_intro":"MedChemExpress（MCE）成立于2013年，总部位于上海，是中国领先的科研试剂供应商，产品覆盖信号通路、表观遗传学及免疫学。公司以\"高性价比+快速物流\"著称，拥有超10万种化合物库，其中CpG ODN系列采用固相合成技术，纯度≥98%。MCE注重品控，每批次提供HPLC和质谱报告，且支持小包装定制（100μg起售）。创始人团队来自中科院和药明康德，深谙中国科研用户痛点——价格敏感、急需用货。MCE在国产替代浪潮中迅速崛起，市场份额已跻身前三。","product_intro":"CpG ODN 2006是人特异性B型CpG ODN，序列为5'-TCGTCGTTTTGTCGTTTTGTCGTT-3'，全硫代修饰。核心卖点：① 高效激活人TLR9，诱导pDC分泌IFN-α；② 价格仅为进口品牌的60%；③ 现货供应，48小时直达。适用场景：人PBMC刺激实验、疫苗佐剂筛选、肿瘤免疫共培养。与InvivoGen相比，MCE在纯度上略低（95% vs 98%），但性价比突出，尤其适合预实验和大规模筛选。用户反馈其活性与进口品牌无显著差异。","key_specs":{"序列":"5'-TCGTCGTTTTGTCGTTTTGTCGTT-3'（B型CpG ODN）","修饰方式":"全硫代磷酸化","规格":"1 mg（冻干粉）","纯度":"≥98%（HPLC）","内毒素水平":"<1 EU/mg","适用物种":"人、猴"}}
• alt_products：[{"product_name":"CpG ODN 2006 (Human TLR9 Agonist)","brand":"MCE (MedChemExpress)","model":"HY-13510","price":1680},{"product_name":"CpG ODN 1585 (A型，小鼠特异性)","brand":"金斯瑞 (GenScript)","model":"SC1331","price":980}]
• kol_quotes：[]
• scoring_breakdown：[{"source":"word_of_mouth","score":83.8,"weight":0.15,"confidence":0.8,"details":{"source":"word_of_mouth_scores","summary":"综合天猫、小红书及生物论坛评价，用户满意度较高。优点：① 价格亲民，适合经费有限的课题组；② 发货快，常备库存；③ 活性稳定，流式检测TLR9表达效果明显。缺点：① 批次间内毒素水平波动（0.5-1.5 EU/mg），高要求实验需预检；② 溶解后出现少量沉淀（属正常现象，但新手易误判）；③ 缺乏VacciGrade级别，不适用于敏感动物模型。专业评测指出，其诱导IFN-α能力与InvivoGen相当，但IL-6分泌略低。","source_count":4}},{"source":"objective","score":88.72,"weight":0.6,"confidence":0.8,"details":{"rating_avg":4.6,"review_count":510,"wom_score":83.8}},{"source":"user_review","score":92,"weight":0.15,"confidence":1,"details":{"rating_avg":4.6,"review_count":510,"source":"product_reviews_aggregate"}}]
• method_version：v3
• search_visual：null