CpG ODN 1826 (VacciGrade)

评测依据

• review_count：320
• rating_avg：4.8
• brand_reputation：0
• merchant_count：0
• price_range：[2000,4999]
• dimension：best_value
• sources：["京东","天猫"]
• time_range：{"from":"2026-06-25 15:17:17","to":"2026-06-25 15:17:17"}
• intros：{"brand_intro":"InvivoGen 成立于1997年，总部位于法国，是全球领先的先天免疫研究工具供应商。公司专注于TLR激动剂、NLR配体及STING通路相关试剂，其VacciGrade系列专为疫苗佐剂研发设计，采用GMP-like生产流程，内毒素水平低于0.1 EU/μg。创始人Dr. Jean-Marc Cavaillon是先天免疫领域权威科学家，团队坚持\"质量即科学\"的品控理念，每批次均通过功能活性验证。InvivoGen在免疫学耗材市场占据高端地位，尤其CpG ODN产品线被全球超过2000个实验室引用，是业内公认的\"金标准\"。","product_intro":"CpG ODN 1826是小鼠特异性B型CpG寡核苷酸，序列为5'-TCCATGACGTTCCTGACGTT-3'，全硫代磷酸化修饰。核心卖点在于其强效激活TLR9的能力，可诱导Th1型免疫应答，适用于肿瘤免疫、疫苗佐剂及自身免疫病模型研究。与竞品相比，InvivoGen提供VacciGrade级别（超低内毒素）和Grade级别两种规格，满足从细胞实验到动物模型的不同需求。该产品在PubMed中被引用超过800次，是研究小鼠先天免疫的首选工具。","key_specs":{"序列":"5'-TCCATGACGTTCCTGACGTT-3'（B型CpG ODN）","修饰方式":"全硫代磷酸化（nuclease-resistant）","规格":"1 mg（冻干粉）","纯度":">95%（HPLC检测）","内毒素水平":"<0.1 EU/mg（VacciGrade级）","适用物种":"小鼠（C57BL/6、BALB/c等）"}}
• alt_products：[{"product_name":"CpG ODN 1826 (VacciGrade)","brand":"InvivoGen","model":"tlrl-1826-1","price":2850},{"product_name":"CpG ODN 2395 (C型，小鼠/人通用)","brand":"Sigma-Aldrich (Merck)","model":"SML2345","price":4200}]
• kol_quotes：[]
• scoring_breakdown：[{"source":"word_of_mouth","score":94.1,"weight":0.15,"confidence":0.8,"details":{"source":"word_of_mouth_scores","summary":"综合丁香通、京东及学术论坛评价，用户普遍认可其批次稳定性和生物活性。优点包括：① 激活TLR9效率高，ELISA检测IFN-α/IL-12重复性好；② 内毒素控制严格，动物实验无意外炎症反应；③ 附详细质检报告，便于论文发表。缺点：① 价格较高（约2850元/mg），小课题组预算压力大；② 冻干粉复溶后需-20℃保存，反复冻融影响活性；③ 仅限小鼠使用，人源实验需另购ODN 2006。专业评测指出，其纯度优于Sigma-Aldrich同类产品，但溶解速度略慢。","source_count":2}},{"source":"objective","score":88.03216572190729,"weight":0.6,"confidence":0.5,"details":{"rating_avg":4.8,"price":2850,"wom_score":94.1}},{"source":"user_review","score":96,"weight":0.15,"confidence":1,"details":{"rating_avg":4.8,"review_count":320,"source":"product_reviews_aggregate"}}]
• method_version：v3
• search_visual：null